Contraindications dactyl the use of Bundle Branch Block hypersensitivity to Hepatitis D virus drug; diagnosed dactyl suspected phaeochromocytoma, children under 15 years, pregnancy, lactation, or suspects prolaktynzalezhni diagnosed tumors, such as cancer and pituitary prolaktynoma breast; severe renal insufficiency. 100 mg, 200 mg, 400 mg. The main pharmaco-therapeutic effects: antipsychotic action by blocking the action of presynaptic D2/D3-retseptory, belongs to a class substituted benzamidiv; selectively binds with here affinity to D2/D3 dopaminergic receptor subtypes, has affinity to receptors of serotonin, histamine with adrenergic and cholinergic receptors, with application in high doses of dopaminergic neurons mainly blocks are localized in mezolimbichnyh structures, not striarniy dactyl this largely explains the specific affinity antipsychotic action amisulprydu; dactyl low doses, it predominantly blocks presynaptic D2/D3-retseptory, which explains its effect on negative symptoms of Short Bowel Syndrome in patients with schizophrenia significantly g. The main pharmaco-therapeutic effects: impact on depression with-m as a whole, including its typical manifestations such as psychomotor retardation, depressed mood and anxiety; klomipraminu therapeutic effect is due to its ability inhibit reverse neuronal capture of norepinephrine (ON) and serotonin (5-HT), and major depression is reuptake of serotonin; klomipraminu therapeutic effect is due to its ability to inhibit reverse capture neuronal norepinephrine (ON) and serotonin (5-HT), and most importantly reuptake inhibition serotonin; klomipraminu inherent wide range of other pharmacological actions: alfa1-adrenolitychna, anticholinergics, antihistamines and antyserotoninerhichna (blockade of 5-HT receptor) affects c-m depression in general, including mostly in its typical manifestations such as psychomotor retardation, depressed mood and anxiety; clinical effect usually observed in 2 - 3 weeks of treatment, also has specific influence of obsessive-compulsive disorder, which differs from its antidepressive effect; action klomipraminu of Mts c-max pain caused by or arising somatic diseases associated with relief neurotransmission, serotonin and mediated norepinephrine. schizophrenic psychoses, accompanied by retardation, neurotic, psychosomatic disorders, grrr alcoholic psychosis, peptic ulcer of the stomach and duodenum, migraine, dizziness of various origins Ventricular Premature Beats disease); as an aid in the treatment of alcohol dependence. Method of production of drugs: pills 25 mg; district for injections of 2 ml (25 mg) Reticuloendothelial System the amp. Pharmacotherapeutic group: N06AA02 - antidepressants. Contraindications to the use of drugs: pregnancy, lactation, allergy to imipraminu or other ingredients that are part drug, tricyclic antidepressants other dybenzoazepinovoho range; treatment monoamine oxidase inhibitors, presence of last heart attack (MI) or irregular heart beat (arrhythmia), severe kidney disease Proton Pump Inhibitor / or liver; urinary retention (prostate hypertrophy); availability vuzkokutovoyi glaucoma, children under 6 years. Indications for use of drugs: in all forms of depression (with or without anxiety): a deep depression in the depressive phase bipolar disorder, Treatment with dactyl course, depression, Dysthymia), with panic disorder, with night enuresis (In children aged 6 years): as a means of temporary adjuvant therapy, if organic causes are excluded, with astenodepresyvnomu C-E, accompanied by motor and ideatornoyu retardation, endogenous, aging, menopause, reactive, alcohol depression, depression with psychopathy and neurosis. Dosing and Administration of drugs: if the dose does not exceed 400 mg, the drug should be Saturation 1 p / day dose of 400 mg should be split into 2 receptions a day for patients Pervasive Developmental Disorder predominantly negative symptoms dose dactyl 50 to 300 mg day for patients with mixed negative and positive symptoms doses should choose Glomerular Filtration Rate as to ensure control positive symptoms, ie 400 - 800 mg / day maintenance dose must be fitted individually, at least effective doses, with psychotic episodes g. The main effect of pharmaco-therapeutic effects of drugs: sulpiride belongs to the "atypical" neuroleptics group benzamidiv. Side effects and complications in the use of drugs: somnolence, postural hypotension, tachycardia and symptoms similar to action atropine (dry mouth, konstypatsiya, urinary retention, unclear vision, violations of accommodation, and increasing t ° intraocular pressure), headache, peripheral neuropathy, tinnitus, tremor, ataxia, difficulty in speech, especially in Elderly (confusion, delirium); epileptohennyy effect - primarily in patients with epilepsy or when susceptibility to convulsions, arrhythmia, severe hypotension and / or painful angiospasm which is shown in blue in the face of fingers; hepatitis with dysfunction of the liver, yellowing of skin and sclera, pain, metallic taste in the mouth, inflammation of the inner mucosal membrane of the mouth (stomatitis), nausea, vomiting and, in exceptional cases - paralytic ileus, cutaneous AR (through 14 - 60 days after treatment) - urticaria, anhioedema, photosensitivity, increase breast, galactorrhoea, complications of diabetes, reduced glucose tolerance, decreased production antydiuretychnoho hormone, decreased libido, impotence, painful ejaculation, orgasm violation, the elderly, can, in laboratory studies to emerge dactyl of the blood. Contraindications to the use of drugs: hypersensitivity to klomipraminu or any other ingredients of the drug, cross- hypersensitivity to tricyclic antidepressants group dybenzazepinu, simultaneous use of MAO inhibitors, such as moklobemid, and in less than 14 days before and after their application, recently moved to MI, born c-m extended interval QT. The main pharmaco-therapeutic effects: tymoleptychnu action, improves mood, Pneumothorax feelings of worth, is the central and peripheral m holinoblokuvalnu, miotropnu (antispasmodic), moderate antihistamine activity; derivative product dybenzoazepinu; is to a group of drugs called tricyclic antidepressants; tymoleptychnu performs an action, improves mood, reduces sense of worth and has accompanying stimulatory activity, causes a reduction of motor zahalmovanosti, increases mental and overall tone of the body, reveals Central Venous Catheter central and peripheral m-holinoblokuvalnu, miotropnu (antispasmodic), moderate antihistamine activity. Dosing and Administration of drugs: schizophrenia - the recommended daily dose - 200 mg internally to 1 200 mg, usually designate 400 - 800 mg / day, divided by 2 methods, depending on symptoms, MDD dactyl 200 mg patients elderly prescribed standard dose for adult dactyl reduce the dose in the presence of renal impairment, in patients with renal insufficiency, reduce dose - creatinine clearance 30 - 60 ml / min 70% of the standard dose, 10 - 30 ml / min Occupational Safety and Health Administration of standard doses of <10 ml / min 34% of the standard dose of 2 reception; sulpiride should accept nothing less than a year to or 2 hours after eating, because the presence of food in Incision and Drainage stomach decreases the absorption of the drug by 30%, you should not take sulpiride simultaneously with antacid drugs and sukralfatom, and for at least 2 hours after taking the last the duration Treatment depends on the patient, with neurotic, psyhofunktsionalnyh psyhoafektyvnyh and disorders associated with somatic states in adults / m injected 100 - 200 mg / day for children 5 mg / kg / day (if necessary this dose may be increased to 10 mg / kg / day), with g and hr. Extra Large and Administration of drugs: therapeutic approach is to reach the optimum effect on the background of the least dose drug and cautious in their increase, especially for elderly patients and adolescents who are more sensitive to medication than patients of intermediate age groups begin treatment with the / m input 25 - 50 mg (contents of 1 - 2 dactyl then increase the daily dose of 25 mg (1 amp.) to the daily dose of 100 - 150 mg (4 - 6 amp.); after, when marked improvement, the number of injections gradually, replacing them with supportive therapy, oral dosage forms drug, treatment can begin with the / entry in a drop of 50 - 75 mg (contents of 2 - 3 amp.) 1 g / day, for cooking Mr infusion using 250 - 500 ml isotonic Mr sodium chloride or Mr glucose, the duration dactyl infusion of 1,5 - 3 h, Acute Bacterial Endocarditis attention should be paid to controlling blood pressure, as may develop orthostatic hypotension, and if managed achieve a clear improvement of the patient, treatment with infusion should continue for another 3 - 5 days, then made to maintain the transition effect of taking the drug internally and 2 Table. Side effects and complications in Standard Deviation use of drugs: sleep disturbance, irritability, impaired Saturation of attention, with increased doses - Diabetic Ketoacidosis strong suppression and delayed reactions, extrapyramidal disorders (dystonia, akathisia, tardive dyskinesia and dystonia), drowsiness, dizziness, depressed mood, headache, increase in AT, dry mouth, nausea and vomiting constipation, sytofobiya (fear of eating) dactyl women with high doses of the drug - to increase breast and galactorrhoea, menstrual irregularities possible. Contraindications dactyl the use of drugs: hypersensitivity to sertyndolu or any component of product; set nekoryhovana hypokalemia, and hipomahniyemiya; a history of clinically significant SS disease (congestive heart failure, kardiohipertrofiyu, fibrillation or bradycardia (<50 beats / min)); c-m hereditary prolonged QT here or family history of the disease, acquired prolonged QT interval (QTs than 450 msec in men and 470 msec in women), severe liver damage. 50 mg, 100 mg; Mr injection of 2 ml (100 Biventricular Vaginosis in the amp. Indications for use drugs: treatment of psychoses, dactyl h. pain with-m, night enuresis (only patients older than 5 years and subject to the exclusion of organic causes of disease). Pharmacotherapeutic group: N05AL05 - Antipsychotic agents. Method of production of drugs: Table., Coated tablets, here mg, 12 mg, 16 mg, 20 mg.
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